Multiprocessing System in an Isolator

Hosokawa Alpine, Augsburg, Germany offers a versatile grinding system installed in an isolator with which it is possible to fulfil the increased demands of the pharmaceutical industry regarding product and personal safety when processing highly active substances.

The multiprocessing system permits realisation of a variety of comminution processes, i.e. impact grinding, impact grinding with integrated classification, grinding in a spiral jet, opposed jet comminution in a fluidised bed as well as superfine classification.

The mill, classifier and metering subassembly is in monobloc design, i.e. made from a solid. All product-contact parts correspond to material quality AISI 316 L with a surface quality of Ra £ 0.8 µm.

The two-chamber isolator is operated under negative pressure and permits the contamination-free processing of toxic products at an "occupational exposure level" OEL of < 1 µg/m3. The a/ß transfer system permits low-contamination product feed and discharge. The system has an integrated WIP cleaning system. The isolator is made completely of stainless steel AISI 316 L with an inside surface quality of Ra £ 0.8 µm.

This multiprocessing system was developed in cooperation with a renowned global pharmaceutical enterprise and was designed and manufactured completely within the Hosokawa corporate group.

For further information, please contact:

HOSOKAWA MICRON Ltd. (UK)
Rivington Road,
Whitehouse Industrial Estate
Runcorn
Cheshire
WA7 3DS
UK

Tel: +44 1928 755 100
Fax: +44 1928 714 325

E-Mail: powder@hmluk.hosokawa.com
Web: www.hosokawa.co.uk

HOSOKAWA ALPINE Aktiengesellschaft
Pharmaceuticals Division
Peter-Doerfler-Strasse 13-25,
D-86199 Augsburg, Germany

Tel.: +49 821 59 06-283
Fax: +49 821 59 06-620

e-mail: pharma@alpine.hosokawa.com
Website: www.alpinehosokawa.com/engl/